CSEL Science promotes both project-based and model-based learning through investigations.

Session 7.3: Sickle Cell Inheritance Lab also illustrates both project-based and model-based learning through an investigation of sickle cell inheritance.

Students are tasked with investigating how a girl inherited the sickle cell gene and whether her future children are at risk of sickle cell anemia. Students analyze a real-world case, construct Punnett squares, and develop pedigree models to explain how a genetic trait is transmitted across generations.

This sustained inquiry reflects core features of project-based learning, including collaborative analysis of evidence and application of genetics concepts to an authentic scenario. It also exemplifies model-based learning, as students generate and revise representational models to explain inheritance patterns and predict outcomes.

Together, these activities position students as sensemakers using models to explain a meaningful biological phenomenon.